The default assumption of the damage on the below Innate Attack lines is to represent most weapon's maximum damage dealing capability. Thus, this can handle anything with a minimum ST of 23 or less. This should be more than sufficient for most non-giant-sized weapons. For larger weapons, a customized version of this spell (requiring the appropriate research and expense) with a higher damage potential is required.

Affliction [122] 
    Advantage [+1111%] 
        Wounding [108.64] 
            Innate Attack (Cutting) 10d+10 [10.92] 
            Innate Attack (Impaling) 10d+10 [62.4] 
            Innate Attack (Small Piercing) 10d+10 [4.68] 
            Innate Attack (Piercing) 10d+10 [7.8] 
            Innate Attack (Large Piercing) 10d+10 [9.36] 
            Innate Attack (Huge Piercing) 10d+10 [12.48] 
            Cosmic (Wounds to Living Creatures Can Only Heal Naturally) [+60%] 
                Must Be Wielded (Anyone can use) [-30%] 
                Magical [-10%] 
            No Base [-100%] 
            Alternate Ability [x1/5] 
                On all but Impaling 
        Innate Attack (Toxic) 1 HP [2.4] 
            Follow-Up (Cutting, Impaling and Piercing) [+0%] 
            Delay (Fixed, 1 second) [+0%] 
                This can be stopped by bandaging the wound 
            Cosmic (Wounds to Living Creatures Can Only Heal Naturally) [+100%] 
    Malediction (As Regular Spell) [+100%] 
    Based on Activation Roll [+5%] 
    Melee Attack (Reach C, No Parry) [-35%] 
    Only Works on Weapons [-40%] 
    Magical [-10%] 
    Spell Components [-20%] 
        Must say "penetrate" in Latin 
        Must gesture with hands 
Level 2 [123] 
    Add Cyclic (1 second interval) 1 to Innate Attack (Toxic) [+12%] 
        This can be stopped by bandaging the wound 
Levels 3-10 [124/125/126/128/129/130/131/132] 
    Increase Cyclic on Innate Attack (Toxic) by 1 [+12%] 
Projectile Option [+1] 
    Area Effect (2 Yard Radius) [+50%] 
    Add Only Works on a Handful [-30%] 
    Change Only Works on Weapons to Only Works on Projectiles [-10%] 
        Anything that can be thrown or can be fired from a weapon 
        Rocks, darts, arrows, etc. 
        Throwing axes don't count; they're also melee weapons